| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-849
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate |
2001-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_373743c77991a39219a90816c21c758a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9121614b9a068ca7862669c49b7046e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b1c3df531f73edd36103e19f0da7d7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e87238d6a4a367a1812d043a6fc4ed4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c363a1385944c67969711eb32dc4b456
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7ccbaf04a66a0b06c17905de85ea9a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c16d7294704921ee45ee905ec6b0280
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c3e84c97cc5ab7b8bdc8e1c806778c7 |
| publicationDate |
2003-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003224468-A1 |
| titleOfInvention |
Treatment or prophylaxis of diseases caused by pilus-forming bacteria |
| abstract |
Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infectivity of the bacteria is diminished. Also disclosed are methods for screening for drugs as well as methods for the de novo design of such drugs, methods which rely on novel computer drug modelling methods involving an approximative calculation of binding free energy between macromolecules. Finally, novel pyranosides which are believed to be capable of interacting with periplasmic molecular chaperones are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008171706-A1 |
| priorityDate |
1993-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |