| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10345
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-6018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10322 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 |
| filingDate |
2003-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97512c6cf09e74594184e3fcbe5cb0e4 |
| publicationDate |
2003-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003219899-A1 |
| titleOfInvention |
Mosaic adenoviral vectors |
| abstract |
The present invention provides adenoviral vectors (Ad) that incorporate multiple distinct capsid modifications in a single virus particle, resulting in Ad that have improved gene delivery capacities and/or vector function. The capsid modifications include (a) addition of a heterologous targeting ligand; (b) a fiber shaft with altered length; (c) capsid modification that alters the charge of the adenoviral vector; and (d) replacing the capsid proteins with capsid proteins from another serotype. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11077156-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11746334-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11485767-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008012682-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107267469-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014199285-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11401529-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107365364-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009544303-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11130968-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8163544-B2 |
| priorityDate |
2001-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |