abstract |
The invention relates to a process for the production of compounds of general formula (I), wherein R 1 is a —NH-tert-butyl group or a 4-methyl-piperidino group, by bioconversion of compounds of general formula (II), wherein R 1 is as described above, using a biocatalyst having steroid-Δ 1 -dehydrogenase enzyme activity, wherein the activity of the enzyme needed for the bioconversion is produced by induction. |