Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb66d9373d09efad73c142762f6dfb00 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-001 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
2003-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58d29f356b7b8930535f0d16bbf9f609 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75d7be74bb8c4a6c9666db1f9adfb9b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee05ad94aa3ce747c6a2e911c045f570 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddc90b3818f33045edf8f82508a30ef6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e66a923610c70f01b454e625354c15a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f0e7fcc30e14c82d14d7f32738f8c17 |
publicationDate |
2003-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2003211979-A1 |
titleOfInvention |
FAP-activated anti-tumor compounds |
abstract |
The invention relates to a prodrug that is capable of being converted into a drug by the catalytic action of human fibroblast activation protein (FAPα), said prodrug is chemically stable under physiological conditions and can be used for the manufacture of physically stable aqueous formulations. It has a cleavage site which is recognised by FAPα, and the drug released by the enzymatic activity of FAPα is cytotoxic or cytostatic under physiological conditions. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7399869-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003119391-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008280856-A1 |
priorityDate |
2002-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |