Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-02 |
filingDate |
2003-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_327c0b730afe9bd7790ff10c646c983e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66bd54d15cb5904b0958c82111fdd97f |
publicationDate |
2003-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2003211158-A1 |
titleOfInvention |
Microgel particles for the delivery of bioactive materials |
abstract |
Novel microgels, microparticles and related polymeric materials capable of delivering bioactive materials to cells for use as vaccines or therapeutic agents. The materials are made using a crosslinker molecule that contains a linkage cleavable under mild acidic conditions. The crosslinker molecule is exemplified by a bisacryloyl acetal crosslinker. The new materials have the common characteristic of being able to degrade by acid hydrolysis under conditions commonly found within the endosomal or lysosomal compartments of cells thereby releasing their payload within the cell. The materials can also be used for the delivery of therapeutics to the acidic regions of tumors and sites of inflammation. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007281870-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7306040-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007277981-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007237821-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8203132-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008095699-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009281383-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009086908-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7517914-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008075667-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009093700-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8660631-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009159805-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9113784-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010220836-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009114860-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010046076-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021042043-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010208348-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8050735-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8041409-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7993749-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009324048-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014052465-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010022866-A1 |
priorityDate |
2002-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |