| abstract |
The present invention discloses the cloning of a new cDNA, HGFIN, from stimulated BM stromal cells that was retrieved with a probe specific for the neurokinin-1 (NK-1) receptor. The novel gene, HGFIN, encodes a protein receptor that is involved in the regulation of hematopoietic proliferation and differentiation. HGFIN is implicated in the treatment of hyperproliferative disorders, particularly cancer, because it acts to suppress the proliferating cells. |