| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4756 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B1-00 |
| filingDate |
1999-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ee190889346838d7ce5004be4283ecd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cfd2e30fb63f3e3dc838ffbd4532155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11fa6d3fe3be454018633cddd0c3d246 |
| publicationDate |
2003-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003199020-A1 |
| titleOfInvention |
Chimeric heteromultimer adhesins |
| abstract |
Novel chimeric heteromultimer adhesins that bind the ligand of natural heteromultimeric receptors and uses therefor are disclosed. The chimeric molecules of the heteromultimer adhesins comprise an extracellular domain of a heteromultimeric receptor monomer and a multimerization domain for the stable interaction of the chimeric molecules in the adhesin. Specifically disclosed are heteromultimeric adhesins comprising the extracellular domains of ErbB2 and ErbB3 or ErbB2 and ErbB4. The chimeric ErbB heteromultimer adhesins of the present invention are useful as competitive antagonists or agonists of a neuregulin for the treatment of diseases such as various cancers. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10184006-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10273304-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7846440-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8623592-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8133976-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8691225-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8895001-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8961966-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009291085-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010266584-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011123523-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009258005-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011159513-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009304590-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014051567-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011027291-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9518130-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9487588-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9688761-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010196404-A1 |
| priorityDate |
1996-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |