| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B25-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2003-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdc495d3ee3e6a9c9d43370ecd62d7ec |
| publicationDate |
2003-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003198987-A1 |
| titleOfInvention |
Methods for designing oligo-probes with high hybridization efficiency and high antisense activity |
| abstract |
Methods are disclosed for selecting oligonucleotide probes with high target affinity. These methods include combining several types of thermodynamic criteria or nucleotide composition criteria for the selection of efficient oligonucleotide probes. The development of these methods was based on statistical analysis of datasets of hybridization or antisense experiments. The methods described here demonstrated variable efficiency in practice, however any or all of them can be used depending on the task of probe design. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005049851-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005049851-A2 |
| priorityDate |
2002-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |