| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16222 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56988 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16 |
| filingDate |
2003-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_108e14acad7aeb5b5f02b6b5f6d69557
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac9a93adf94f4be78a7b96aef27a65e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c57a84e8add1dc2939e8c18da4846c3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fdca10276e46f0dcfe4514070b1cdab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d0211f0389012f93500bb14c51decd9 |
| publicationDate |
2003-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003198648-A1 |
| titleOfInvention |
Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA |
| abstract |
The present invention relates to methods of identifying a molecule from a library of molecules that inhibits binding of human immunodeficiency virus nucleocapsid 7 polypeptide (NCp7) to an oligonucleotide which comprises admixing an NCp7 polypeptide with at one labeled HIV-1 psi-site oligonucleotide and an amount of the molecule to be tested under binding conditions; and determining the amount of oligonucleotide bound to the NCp7 polypeptide, wherein a decrease in the amount of oligonucleotide bound in the presence of the molecule compared with the amount of oligonucleotide bound in the absence of the molecule indicates that the molecule inhibits binding of NCp7 polypeptide to the oligonucleotide. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020504090-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7221865-B2 |
| priorityDate |
2002-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |