| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3873abaff397acbfffa1595a12cfef41 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4354 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate |
2003-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2a74a91c6061668999a1146e1cb9df9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1887d5f241b1498ef335bb6b96fabcd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_599026625e2d2a51e24573c4bdf68b96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44e0cfe032eca53d8b30e3984d5c315c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b8ee91e041dec158c8e0d5593e1dfe8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dce2dc0577d347426e856ec607990ddd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c1842a26984506d8bdead1d79b531a6 |
| publicationDate |
2003-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003190666-A1 |
| titleOfInvention |
Method for detecting and reversing resistance to macrocyclic lactone compounds |
| abstract |
This invention describes novel purified and isolated nucleic acid molecules or the fragments thereof, extracted from nematode or arthropod pests or recombinant, which encode P-glycoprotein homologs and regulate resistance to the macrocyclic lactone compounds. The invention further relates to the new P-glycoprotein homolog expression product of these nucleic acids. Also described herein are methods for detecting the gene encoding for resistance to the macrocyclic lactone compounds in nematode or arthropod pests which comprise comparing the nucleic acids extracted from a pest specimen to the nucleic acids encoding for resistance and the nucleic acids encoding for susceptibility to the macrocyclic lactone compounds. Lastly, the present invention is also drawn to methods and compositions for increasing the efficacy of the macrocyclic lactone compounds against resistant nematode or resistant arthropod pests which comprise administering to a mammal or applying to crops and the like a pesticidal enhancing effective amount of a multidrug resistance reversing agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008103048-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021360924-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9155306-B2 |
| priorityDate |
1997-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |