Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2517-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2517-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-873 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1276 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-873 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
2002-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c0848727068c9030c5ae2066f81c3cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f142f7e3b711b68501389dc8b797284 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a406c83a1250604555e25547d070156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4af13331882d55cb913f446132d8b2a4 |
publicationDate |
2003-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2003175967-A1 |
titleOfInvention |
Vectors for telomerizing nuclear donor cells and improving the efficiency of nuclear transfer |
abstract |
This disclosure provides a system for creating cloned cells and embryos that are genetically modified. Cells are treated to increase expression of telomerase and potentially extend replicative capacity. One or more genetic modifications is made to inactivate a gene or confer desirable features, growing and selecting the cells as needed. The modified nucleus can then be transferred to a suitable recipient cell, which can then be used to grow an embryo with the conferred attributes. This technology makes it possible to create embryos, animals and embryonic cell lines with multiple genetic modifications, including homozygously inactivated genes and gene substitutions. |
priorityDate |
2001-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |