abstract |
There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the ACK1 gene, which are amplified breast and/or ovarian and/or prostate cancer genes. The ACK1 gene, its expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or vaccine; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy. |