http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003166938-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
| filingDate | 2002-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dfb453aadc17efcb1825087af69f778 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da0e95ea95a3cdd8f11cdf9a473a17a8 |
| publicationDate | 2003-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003166938-A1 |
| titleOfInvention | Preparation of paroxetine involving novel intermediates |
| abstract | Disclosed are processes for preparing novel carbamate intermediates of paroxetine comprising dealkylating N-alkylparoxetine by reaction thereof with a haloalkyl ester of a haloformic acid, in a suitable organic solvent. Also disclosed are processes for preparing paroxetine comprising hydrolyzing the novel carbamate intermediates in a suitable solvent. Paroxetine prepared by the above processes can be neutralized with hydrogen chloride and crystallized as paroxetine hydrochloride anhydrous, hemihydrate or as a solvate of isopropanol. The invention is further directed to the novel carbamate intermediates formed by the disclosed processes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102718756-A |
| priorityDate | 2002-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.