http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003166005-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91245 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 |
filingDate | 2001-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87521ad2c54654964ee0565504f38b75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e56026ac7d3591b36fe94483d204289 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1c5cdabff232a3682398a4391f242ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a3140c212c53066f15bbbfb9da781ce |
publicationDate | 2003-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2003166005-A1 |
titleOfInvention | Test system for determining the activity of cyclo-nucleotide-dependent protein kinases and vasp phosphatases |
abstract | The invention relates to an HTS-appropriate test system for detecting the activity of cyclo-nucleotide-dependent protein kinases (cNPK) containing: a) at least one test compound; b) at least one appropriate cNPK substrate; c) at least one composition, which is to be incubated and which contains cNPK and ATP, optionally, phosphorylation reaction stoppers, and; d) an appropriate detection system for quantifying the phosphorylation of the cNPK substrate. The invention also relates to an HTS-appropriate test system for detecting the activity of VASP phosphatases containing: e) at least one test compound; f) at least one appropriate VASP phosphatase substrate; g) at least one composition, which is to be incubated and which contains VASP phosphatase, and; h) an appropriate detection system for quantifying the dephosphorylation of the VASP phosphatase substrate. The described test systems can be used for locating compounds, which modulate the activity of a cNPK or of a VASP phosphatase, from chemical or natural substance libraries. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107709996-A |
priorityDate | 2000-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 193.