http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003162982-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-732 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D301-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-732 |
| filingDate | 2001-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8e78c24935e92b8d939d1c2de5f7155 |
| publicationDate | 2003-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003162982-A1 |
| titleOfInvention | Method for the enantioselective preparation of 3,3-diphenyl-2,3-epoxy propionic acid esters |
| abstract | The invention relates to a method for the enantioselective preparation of the glycide ester (I) by (a) dihydroxylating a corresponding 3-phenyl cinnamic acid ester (II) by osmium (VIII) oxide catalysis in the presence of a Sharpless ligand and an oxidant to give a dihydroxy ester (III), (b) selectively converting the hydroxy function in the 2 position of the dihydroxy ester (III) to a leaving group, (c) intramolecularly substituting the leaving group by the hydroxy function in the 3 position to the glycide ester (I). In formulae (I), (II), and (III), R 1 represents C 1 -C 10 alkyl, aryl or arylalkyl, which can optionally be substituted, and R 2 represents C 1 -C 10 alkyl, aryl, arylalkyl, halogen, C 1 -C 10 alkoxy, acyloxy or amide, which can be optionally substituted, and n is 0 to 5. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103709106-A |
| priorityDate | 2000-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.