Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1641 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-04 |
filingDate |
2002-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebc67933e202096808cad5478a0c7a76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca1707403a563579004b5da688cc8503 |
publicationDate |
2003-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2003152623-A1 |
titleOfInvention |
Responsive microgel and methods related thereto |
abstract |
A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked homopolymeric ionizable monomers wherein the ionizable network is covalently attached to an amphiphilic copolymer to form a plurality of ‘dangling chains’ and wherein the ‘dangling chains’ of amphiphilic copolymer form immobile micelle-like aggregates in aqueous solution. A responsive microgel is further provided that comprises at least one therapeutic entity and delivers a substantially linear and sustained release of the therapeutic entity under physiological conditions. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7005143-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9283281-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8425933-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114768545-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8703186-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9533051-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009170876-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8182836-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005094792-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003203011-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007166383-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007149762-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006039982-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10336923-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015018308-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009012462-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111494304-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9314524-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113968948-A |
priorityDate |
2002-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |