http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003144254-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d7463c209152681d030f21b4c09659d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-559 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-559 |
| filingDate | 2003-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59bb946edb8ad4223d3d0a2d5a071cec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f29ea61ba38e4c08ea755c253ca47c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1acdd93d1f986c96dcc4090f1f4adf13 |
| publicationDate | 2003-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003144254-A1 |
| titleOfInvention | 3, 7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| abstract | The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective amount of a compound represented by the general formula I; n n n wherein hatched lines represent the α configuration, a triangle represents the β configuration, a wavy line represents the α configuration or the β configuration and a dotted line represents the presence or absence of a double bond; n A and B are independently selected from the group consisting of O, S and CH 2 ; n provided that at least one of A or B is S; n D represents a covalent bond or CH 2 , O, S or NH; n X is CO 2 R, CONR 2 , CH 2 OR, P(O)(OR) 2 , CONRSO 2 R SONR 2 or n n n Y is O, OH, OCOR 2 , halogen or cyano; n Z is CH 2 or a covalent bond; n R is H or R 2 ; n R 1 is H R 2 , phenyl, or COR 2 ; n R 2 is C 1 -C 5 lower alkyl or alkenyl and R 3 is benzothienyl, benzofuranyl, naphthyl or substituted derivatives thereof, wherein the substituents maybe selected from the group consisting of C 1 -C 5 alkyl, halogen, CF 3 , CN, NO 2 , NR 2 , CO 2 R and OR. |
| priorityDate | 2001-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 254.