| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac9442e962452275a63c777abad46223 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0623 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-877
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0797
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate |
2000-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ebe99043316bb5e2b78d2ce289a1f0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f46b7e9890f7b08bc837e7ce1b39f94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e848289bc7a7d616d63ca2013d8c6369
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2acf7edb49c07d2620e490f796c36047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d7d4c596a20a9cc624b77ad04068832 |
| publicationDate |
2003-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003143737-A1 |
| titleOfInvention |
Long-term cell-culture compositions and genetically modified animals derived therefrom |
| abstract |
The present invention generally relates to neural stem cells, preferably foetal neural stem cells and their progeny thereof. The present invention provides methods of isolating, culturing and propagating neural stem cells preferably foetal neural stem cells and the development of neural stem cell lines and lineages. The present invention also relates to the use of neural stem cells and somatic cells (eg rat fetal fibroblasts) and cells expressing the telomerase catalytic component (TERT) for gene targeting and gene knockout experiments and for producing genetically modified animals. n In a first aspect of the present invention there is provided a cellular composition comprising one or more cells having a property characteristic of a neural stem cell and wherein said neural stem cell is capable of long term culture. Preferably the cells have a property characteristic of a foetal neural stem cell. n In another aspect of the present invention there is provided a method of producing an animal, said method comprising introducing a continuously growing donor cell nucleus from a continuously growing donor cell into an oocyte or embryo and allowing the resulting embryo to mature and to preferably develop to a foetus or an adult animal. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7416888-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7419827-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003134422-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101124319-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9394521-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005090004-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009263357-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10184112-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010279412-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006104959-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005170506-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011212523-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9074176-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006067918-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10131877-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1645626-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7666672-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008118479-A1 |
| priorityDate |
1999-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |