http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003139393-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 |
| filingDate | 2000-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d26b0c243147f9004a80ee7aff4d8b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d69bd73ca38f97ce25210285c2c1d230 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c04169724cd35c8fd073360e4f5f5ca |
| publicationDate | 2003-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003139393-A1 |
| titleOfInvention | Substituted homopiperidinyl benzimidazole analogues as fundic relaxants |
| abstract | The present invention relates to compounds of formula (I) n n n their prodrugs, N-oxides, addition salts, quaternary amines and stereochemically isomeric forms, wherein the bivalent radical —{circle over (A)}— represents a saturated or an unsaturated homopiperidinyl having one double bond, and wherein said bivalent radical —{circle over (A)}— is substituted with R 2 being hydrogen, hydroxy, C 1-4 alkyl, or C 1-4 alkyloxy; -a 1 =a 2 -a 3 =a 4 - represents an optionally substituted bivalent radical; R 1 is hydrogen, C 1-6 alkyl, aryl 1 , C 1-6 alkyl substituted with aryl 1 , C 1-4 alkyloxycarbonyl, aryl 1 carbonyl, aryl 1 C 1-6 alkylarbonyl C 1-4 alkylcarbonyl, trifluoromethyl, trifluoromethylcarbonyl, C 1-6 alkylsulfonyl, aryl 1 sulfonyl, methanesulfonyl, benzenesulfonyl, trifluoromethanesulfonyl, dimethylsulfamoyl; X represents O, S or NR 3 , wherein R 3 is hydrogen, C 1-6 alkyl, methanesulfonyl, benzenesulfonyl, trifluoromethanesulfonyl, dimethylsulfamoyl, C 1-4 alkyl substituted with aryl 2 and optionally with hydroxy, C 1-4 alkylcarbonylC 1-4 alkyl substituted with aryl 2 ; aryl 1 is optionally substituted phenyl, optionally substituted pyridinyl, naphthyl, quinolinyl, or 1,3-benzodioxolyl; aryl 2 is optionally substituted phenyl; fundic relaxating activity. Processes for preparing said products, formulations comprising said products and their use as a medicine are disclosed, in particular for treating dyspeptic symptoms, irritable bowel syndrome and other conditions related to a hampered or impaired relaxation of the fundus. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010004260-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7994173-B2 |
| priorityDate | 1999-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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