http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003138960-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-72 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-72 |
filingDate | 2002-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62428ae9b30386164e352de20b793efd |
publicationDate | 2003-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2003138960-A1 |
titleOfInvention | Quality control material for reagentless measurement of analytes |
abstract | The present invention provides a method for monitoring degradation of Hb-based blood substitutes, in a sample. This method comprises determining a concentration of met-Hb within the sample, by applying a calibration algorithm for met-Hb to an absorbance obtained from the sample at one or more than one wavelengths, and using the concentration of met-Hb, as a measurement of degradation of the Hb-based blood substitutes. Using this assay, a concentration of met-Hb that is equal to or greater than 3% may be used as an indicator of degradation of Hb. Alternatively, by obtaining samples over a period of time, the concentration of met-Hb and the concentration of Hb-based blood substitute may be determined in each of these samples, and an increase in the concentration of met-Hb over the period of time is an indicator of degradation of Hb. The sample may be a whole blood sample, a serum sample, or a plasma sample obtained from a patient transfused with one or more than one Hb-based blood substitutes, a stock Hb-based blood substitute sample, or a body part of a patient. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003027341-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6689612-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012005150-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8645306-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111203877-A |
priorityDate | 2001-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.