Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-26 |
filingDate |
2002-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69b6f8b30aeba84d09fcb8902aa30b24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_711f81ec5ce09bb1264a0fa0ae9fa18a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a32d35914af3cd49913202edbaa6938a |
publicationDate |
2003-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2003138496-A1 |
titleOfInvention |
Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
abstract |
The present invention provides a drug delivery system for the oral administration of a hydrophobic active ingredient. The active ingredient's post-ingestion dissolution rate and its corresponding bioavailability can be optimized by intimately mixing a micronized hydrophobic drug with suitably sized inert particles to a dispersion that will facilitate desired bioavailability. In a particular embodiment, the hydrophobic active ingredient is fenofibrate. Suitably sized inert particles include microcrystalline cellulose and lactose. Dispersion may be monitored by microscopic visualization. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9107832-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9314447-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014091318-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006141052-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003224059-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10342825-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006141051-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9782434-B2 |
priorityDate |
2000-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |