http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003129729-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18651 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18451 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-525 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-115 |
| filingDate | 2002-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d42ce624b60d743a5afd1694765271ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24440c3b9971279a6a24c9dd6ee21e03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f074e28d93dee8469cdda64713a68469 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c137f4e98e0ea7670a92dfdc005c3384 |
| publicationDate | 2003-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003129729-A1 |
| titleOfInvention | Novel methods for rescue of RNA viruses |
| abstract | This invention relates to improved methods for producing nonsegmented, negative-sense, single-stranded RNA viruses of the Order designated Mononegavirales virus, including embodiments relating to methods of producing such viruses as attenuated and/or infectious viruses, such as Measles virus (MV) and respiratory syncytial virus (RSV). One method for producing a recombinant virus from the Order Mononegavirales comprises (a) in at least one host cell, conducting transfection of a rescue composition which comprises (i) a transcription vector comprising an isolated nucleic acid molecule which comprises polynucleotide sequence encoding a genome or antigenome of a nonsegmented, negative-sense, single stranded RNA virus of the Order Mononegavirales and (ii) at least one expression vector which comprises at least one isolated nucleic acid molecule encoding the trans-acting proteins necessary for encapsidation, transcription and replication; in a host cell under conditions sufficient to permit the co-expression of these vectors and the production of the recombinant virus; (b) heating the transfected rescue composition to an effective heat shock temperature under conditions sufficient to increase the recovery of the recombinant virus; and optionally, (c) harvesting the resulting recombinant virus. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111849927-A |
| priorityDate | 1998-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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