http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003124151-A1

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filingDate 2002-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d44760873fcd7d58b519bfada9cdf1c
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publicationDate 2003-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2003124151-A1
titleOfInvention Pamidronate solution
abstract A stable injectable solution containing pamidronate and a method for preparing a therapeutic aqueous disodium pamidronate solution. The method comprises preparing a slurry of pamidronic acid in water, combining aqueous sodium hydroxide with the slurry in an amount about 2:1 molar ratio of sodium hydroxide to parnidronic acid to yield a solution of disodium pamidronate having visual clarity and a pH of about 6.5, and packaging the solution in sealed containers. A unit dosage form including the solution and a vial or ampule comprising the unit dosage form are also described.
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