http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003114438-A1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 |
filingDate | 2002-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d18a8175e02bb9332b42827a4cf8afd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33c25e9fff21c7aed9e9ee978e83b7d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f47f71000392beef4a47a85e266624db |
publicationDate | 2003-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2003114438-A1 |
titleOfInvention | Lactam derivatives as antiarrhythmic agents |
abstract | Lactam derivatives of the formula n n n where n X is -C(=O)NR 3′ -, -NR 3′ C(=O)-, -C(=NCN)NR 3′ -, -NR 3 ′C(=NCN)-, -CH 2 NR 3′ -, -CH(alkyl)NR 3′ -, -CH(COOalkyl)NR 3′ -, -CH(CH 2 OH)NR3 -,-C(CH 2 Oalkyl)-; n R′ is halo, alkyl, cycloalkyl, alkyl(cycloalkyl), aryl, (aryl)alkyl, (aryl)alkenyl, (aryl)alkynyl, O-alkyl, O-alkenyl, O-aryl, O-alky(aryl), O-alkyl(heterocyclo), COO-alkyl, C)-alkyl, CO-amino, CO-substituted amino, alkyl-CO-amino, alkyl-CO-substituted amino, NHCO-alkyl, NHCO-aryl, NHCO-alkyl(aryl), NHCO-alkyl(heterocyclo), N(alkyl)CO-alkyl, N(alkyl)CO-aryl, N(alkyl)CO-heterocyclo, N(alkyl)CO-alkyl(aryl), N(alkyl)CO-alkyl(heterocyclo); n R 2 is hydrogen, alkyl, halo, aryl, (aryl)alkyl, O-alkyl, amino, substituted amino; n R 3 and R 3′ are the same or different and are independently selected from hydrogen, alkyl or alkyl(aryl); n R 4 which can be bonded to a ring carbon or nitrogen, is selected from hydrogen, alkyl, alkenyl, alky(aryl), alkyl(heterocyclo), cycloalkyl, alkyl(cycloalkyl), alkyl-(amino), alkyl-(substituted amino), alkyl-NHCO(alkyl), alkyl-NHCO(aryl), alkyl-NHCO(heterocyclo), alkyl-NHCO(alkylaryl), alkyl-NHCO(alkylheterocyclo); and n is an integer of 0 to 2. These compounds have been found to be useful in the treatment of arrhythmia. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009173672-A |
priorityDate | 1998-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 614.