http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003114385-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate | 2002-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a3e5f8f96ecf5f72533b1650a1c342c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc4c89d6053b42a2b91554f074a4dc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61c87fe219e780b0ec6f6505d589e690 |
| publicationDate | 2003-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003114385-A1 |
| titleOfInvention | Viral enzyme activated prototoxophores and use of same to treat viral infections |
| abstract | A synthetic prototoxophore, which is a relatively non-toxic compound that includes a toxin moiety and a substrate domain for a viral enzyme, is provided. Upon binding of a viral enzyme to the substrate domain, the catalytic activity of the viral enzyme converts the prototoxophore to a toxophore, which is toxic to a cell. Thus, a toxophore also is provided, as is a pharmaceutical composition containing a prototoxophore, and kits containing a prototoxophore. Also provided are methods of using a prototoxophore to reduce or inhibit viral infectivity, and methods of using a prototoxophore to ameliorate the severity of a viral infection in an individual. |
| priorityDate | 2001-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 884.