http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003108944-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3229 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-32 |
| filingDate | 1998-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4328389a76299b13f8ce58c2d5af6acd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74a9ef0e7593a358f6f3ed516bc32bea |
| publicationDate | 2003-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003108944-A1 |
| titleOfInvention | Combinatorial preparations of phosphorus-containing active compounds and intermediates by solid phase synthesis |
| abstract | The invention relates to solid phase processes for the systematic preparation of chemical compounds from the group of the phosphonous or phosphinic acids and/or derivatives thereof and the corresponding substance libraries which can be employed for test purposes, in particular tests for biological activity. The compounds (I) n YR 1 P(═O)(OR 3 )R 2 (I) n in which Y, R 1 , R 2 , R 3 are as defined in claim 1 are prepared by reacting a resin-linker adduct (II) n [resin polymer]-[linker-Z-E 1 -S 1 ] n n in the presence of a suitable Pd catalyst with a phosphinate (III) n A 1 -O—(PHO)A □ (III) n with substitution of the group S 1 to give the compound (IV) n [resin polymer]-[linker-Z-E 1 -P(H)(═O)—OA 1 (IV) n and cleaving the compound (I) after derivatization reactions on the resin from the resin-linker adduct. n The invention also provides the intermediate steps and resin-linked intermediate compounds, and also the substance libraries obtained. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10930822-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019157518-A1 |
| priorityDate | 1997-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 427.