http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003108935-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6823 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2002-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c44044a1d0446e41ee242faeb1f2bdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1eb96d3c0979852aad9bd0778e6b09a |
| publicationDate | 2003-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003108935-A1 |
| titleOfInvention | Probing binding interactions between molecules and nucleic acids by unzipping a nucleic acid molecule double helix |
| abstract | The present invention is directed to a method of identifying the location of a binding site for a binding molecule on a double-stranded nucleic acid molecule, a method of directly determining the equilibrium association constant of a target binding molecule specific to a double-stranded nucleic acid molecule, a method of determining the dynamic force signature of a target binding molecule in relation to a binding site on a double-stranded nucleic acid molecule, a method of identifying whether a target nucleic acid molecule is present in a sample, a method of producing a restriction map, or a method of identifying whether a target protein is present in a sample. The methods are carried out by comparing the force required to unzip the first and second nucleic acid strands of the double-stranded nucleic acid molecule without and (potentially) with a binding molecule bound to the double-stranded nucleic acid molecule. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8218930-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010221734-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008083289-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009208743-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7594443-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016040212-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020056021-A1 |
| priorityDate | 2001-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 184.