| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-825 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6829
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-45 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
1997-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2215f8a5d1770bce79f16b4484bedb72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7943dec01414ede532b85506b5c0b79c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fba2f363470a1c6b583d5f8c71e01a8b |
| publicationDate |
2003-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2003103987-A1 |
| titleOfInvention |
Method of inactivation of ras subfamily proteins and agents therefor |
| abstract |
The invention comprises a method of treating a patient with a disorder, characterized by an activating mutation in the Ras proto-oncogene, comprising contacting cells of said patient with a protein having the toxic activity of Clostridium sordellii toxin LT under conditions favoring inactivating of Ras by glucosylation of Ras′ threonine 35 in said cell. Said protein preferably is an immunotoxin which contains as a toxic domain the catalytic domain of toxin LT. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8007782-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9572843-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8613917-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005039492-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005039492-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005039491-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005039491-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007148135-A1 |
| priorityDate |
1996-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |