Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 |
filingDate |
2001-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09b4e1bff7d09118066d5c3748846ad8 |
publicationDate |
2003-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2003095999-A1 |
titleOfInvention |
Fusogenic properties of saposin C and related proteins and polypeptides for application to transmembrane drug delivery systems |
abstract |
The present invention comprises a method for delivering pharmaceutical agents within and/or through the dermal and mucosal membranes, utilizing a fusogenic protein. The fusogenic protein is associated with a phospholipid membrane, such as a liposome. The liposome contains the pharmaceutical agent. Preferred fusogenic proteins include saposin C and other proteins, polypeptides and peptide analogs derived from saposin C. The active agent contained within the liposome may comprise large biomolecules and/or small organic molecules. This technology can be used for both cosmetic and medicinal applications in which the objective is delivery of the active agent within and/or beneath the biological membrane. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009535348-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109640960-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008051818-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7834147-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008051818-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188698-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101583346-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010507580-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101583346-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007127439-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9271932-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007212403-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109640960-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014111600-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3357490-A1 |
priorityDate |
2000-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |