http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003092742-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2b9dc89cc4ba060cc73bbf0c90bbb78 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-34 |
| filingDate | 1998-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63c89dd383f5ea8e11023f59bb112174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b808e90e4c7344755ad1f88e6303c93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55f680f4a031fad8412c0d4a9e1106ff |
| publicationDate | 2003-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003092742-A1 |
| titleOfInvention | Process for the preparation of thiazolidinedione derivatives |
| abstract | A process for preparing a compound of formula (I) or a tautomeric form thereof or a pharmaceutically acceptable salt thereof, wherein: A 1 represents a substituted or unsubstituted aromatic heterocyclyl group; R 1 represents a hydrogen atom, an alkyl group, an acyl group, an aralkyl group, wherein the aryl moiety may be substituted or unsubstituted, or a substituted or unsubstituted aryl group; A 2 represents a benzene ring having in total up to five substituents; and n represents an integer in the range of from 2 to 6, which process comprises catalytically reducing a compound of formula (II): wherein A 1 , R 1 , A 2 and n are as defined in relation to formula (I), characterized in that the reduction reaction is carried out using a hydrogen pressure above 20 psi; and thereafter if required forming a pharmaceutically acceptable salt and/or a pharmaceutically acceptable solvate of the compound of formula (I). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010081695-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007265313-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7632841-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7435741-B2 |
| priorityDate | 1997-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 132.