Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-515 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01F1-3273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01F1-3218 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01F1-3266 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01F1-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01F1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01F1-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06N3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 |
filingDate |
2002-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ef36e1303667c6e9d4e529a5637fc3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b52050362d1fd101c7084315a073688 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a39c451364294198ff2679bb59e73d1 |
publicationDate |
2003-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2003088237-A1 |
titleOfInvention |
Treatment protocol generation for diseases related to angiogenesis |
abstract |
A computer-implemented method for determining an optimal treatment protocol for a disease related to angiogenesis, comprising creating an angiogenesis model including pro-angiogenesis and anti-angiogenesis factors. Effective vessel density (EVD) is incorporated as a factor regulating switching on and switching off of at least one component in the angiogenesis model. Effects of vasculature maturation and mature vessels destabilization are incorporated. Pro-angiogenesis and anti-angiogenesis factors, which can influence changes in state of a tissue are selected. Effects of drugs in the pro-angiogenesis and anti-angiogenesis factors are incorporated. A plurality of treatment protocols in a protocol space is generated. A best treatment protocol based on a pre-determined criteria. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8150629-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8332158-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007106479-A1 |
priorityDate |
2001-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |