abstract |
The invention provides isolated nucleic acids molecules, designated 6299 nucleic acid molecules, which encode novel zinc carboxypeptidase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 6299 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 6299 gene has been introduced or disrupted. The invention still further provides isolated 6299 proteins, fusion proteins, antigenic peptides and anti-6299 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. |