| abstract |
The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are expressed in thalamus and testes and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions, such as Parkinsonian manifestations (e.g., tremor), neurogenic pain, depression, tinnitis, epilepsy, obsessive-compulsive disorder, dystonia, and spasticity, especially relating to thalamus and testes. |