http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003069432-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-34 |
| filingDate | 2001-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1de2bc161fc2cdaa83cabb40e94273b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeb70806a0a41a383b3c122100b54bdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_374e7688853517fb40ea22174bf5c2d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85da8f45b4a12e27f873e07d3a36f6d2 |
| publicationDate | 2003-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003069432-A1 |
| titleOfInvention | Novel process for preparing 4-substituted-1h-pyrrole-3-carboxylic acid ester |
| abstract | The present invention relates to a novel process for preparing pyrrole ester compounds, which are key intermediates in the preparation of farnesyl transferase inhibitors, an anti-cancer agent. Horner-Emmons reaction of aldehyde compounds provides the corresponding α,β-unsaturated esters, which without any separation and/or purification steps, are treated with toluenesulfonylmethylisocyanate in the presence of base to give pyrrole esters in one-pot fashion. |
| priorityDate | 2000-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.