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filingDate 2002-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_878fd04fc090239a9cc94cb87d040592
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publicationDate 2003-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2003060442-A1
titleOfInvention In situ injection of antigen-presenting cells with genetically enhanced cytokine expression
abstract The use of professional antigen presenting cells genetically modified to enhance expression of an immunostimulatory cytokine is disclosed for the treatment of individuals having tumors or infections. The genetically modified professional antigen presenting cells are injected directly at or near the site of the tumor or infection. Preferred professional antigen presenting cells include dendritic cells, and preferred immunostimulatory cytokines include interleukins such as IL-12.
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