| abstract |
Nucleoside analogues or base analogues having structure (1), where X=O or NH or S, Y=N or CHR 6 or CR 6 , W=N or NR 6 or CHR 6 or CR 6 or S, n=1 or 2; each R 6 is independently H or O or alkyl or alkenyl or alkoxy or aryl or a reporter moiety; where necessary (i.e. when Y and/or W is N or CR 6 where R 6 is not O) a double bond is present between Y and W or W and W, and Q is H or a sugar or a sugar analogue or a nucleic acid backbone or backbone analogue. |