http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003059905-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C259-06
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C259-06
filingDate 2000-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e79cbe901836d18aa9521ba0fa664ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_359cb0adc8acd963e047eed664527d4a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a84535e61193d820891235644836d1d
publicationDate 2003-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2003059905-A1
titleOfInvention Multistage process for the preparation of highly pure deferoxamine mesylate salt
abstract The present invention provides a purification process whereby deferoxamine B produced by a microorganism and in mixture with other polyhydroxamates produced by the microorganism may be converted into its mesylate salt substantially free of the other polyhydroxamates and substantially free of chloride ion. The process includes adsorption and desorption of the deferoxamine B on an adsorption resin, direct precipitation of the deferoxamine free base out of the eluent from the adsorption resin, contacting of the deferoxamine B free base with methanesulfonic acid and isolation of the deferoxamine B mesylate salt by precipitation. This process minimizes decomposition of deferoxamine B.
priorityDate 1999-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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