http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003059905-A1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C259-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C259-06 |
filingDate | 2000-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e79cbe901836d18aa9521ba0fa664ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_359cb0adc8acd963e047eed664527d4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a84535e61193d820891235644836d1d |
publicationDate | 2003-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2003059905-A1 |
titleOfInvention | Multistage process for the preparation of highly pure deferoxamine mesylate salt |
abstract | The present invention provides a purification process whereby deferoxamine B produced by a microorganism and in mixture with other polyhydroxamates produced by the microorganism may be converted into its mesylate salt substantially free of the other polyhydroxamates and substantially free of chloride ion. The process includes adsorption and desorption of the deferoxamine B on an adsorption resin, direct precipitation of the deferoxamine free base out of the eluent from the adsorption resin, contacting of the deferoxamine B free base with methanesulfonic acid and isolation of the deferoxamine B mesylate salt by precipitation. This process minimizes decomposition of deferoxamine B. |
priorityDate | 1999-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.