Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43b6da0b7e905dfc60e7126e7c0db997 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-447 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6862 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2002-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbc1561cf25e44a7dd540f0f3c8252b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dd841f332a0b682afea3b5ebbc8eb02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b96784cce2cd54d389136efb6efb48b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7bf0c6c6d7c738b54c4df48cc0a0395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c097c03b72b8f30743b3ada7f8de811 |
publicationDate |
2003-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2003059810-A1 |
titleOfInvention |
Probe composition and method |
abstract |
Method and composition for detecting one or more selected polynucleotide regions in a target polynucleotide. In the method, a mixture of sequence-specific probes are reacted with the target polynucleotide under hybridization conditions, and the hybridized probes are treated to selectively modify those probes which are bound to the target polynucleotide in a base-specific manner. The resulting labeled probes include a polymer chain which imparts to each different-sequence probe, a distinctive ratio of charge/translational frictional drag, and a detectable label. The labeled probes are fractionated by electrophoresis in a non-sieving matrix, and the presence of one or more selected sequences in the target polynucleotide are detected according to the observed electrophoretic migration rates of the labeled probes in a non-sieving medium. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8597891-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8597890-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8283121-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9206477-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9234241-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8642269-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8288521-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8802373-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8703928-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8624016-B2 |
priorityDate |
1992-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |