| abstract |
An apparatus and method for comparative genomic mapping of a sample and a reference is disclosed that includes an array of oligonucleotides having a surface derived from a selected portion of a genome. A reader capable of producing a signal disposed to detect events that occur at the surface of the array of oligonucleotides and a computer attached to the reader, wherein the computer processes a signal from the reader to determine the relative intensity produced at the array surface and capable of comparing the intensity of the signal from the array to provide map with a resolution of about 20, 30, 50, 100, 200, 500, 1,000, 2,000, 5,000, 20,000, 50,000, 100,000, 200,000, 500,000, 1,000,000, 2,000,000 basepairs. |