http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003040109-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2001-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2f3f25097c2aac56135975786e40750 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d85a085cf31cec6ddfea835d03aa4735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f36fc76dbad4b21147d502d3462947cf |
| publicationDate | 2003-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003040109-A1 |
| titleOfInvention | Chemokines and methods for inducing the differentiation of fibroblasts to myofibroblasts |
| abstract | This invention is based on the discovery that chemokines induce fibroblasts to differentiate to myofibroblasts, which play a critical role in wound healing and are implicated in a number of fibrotic diseases. This activity has been localized to a peptide in the N-terminus of several chemokines. Accordingly, the invention provides polypeptides that induce the differentiation of fibroblasts to myofibroblasts in vitro and in vivo, nucleic acids encoding such polypeptides and related vectors, host cells, and composition containing these components. The invention also encompasses methods for inducing or inhibiting differentiation of fibroblasts to myofibroblasts, in vivo as well as in vitro, and screening methods for identifying other agents that modulate myofibroblast differentiation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011020291-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11267881-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019055776-A3 |
| priorityDate | 2001-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 241.