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publicationNumber US-2003032147-A1
titleOfInvention Rapid and simple process for isolation of circular nucleic acids
abstract A method for separating and/or isolating circular nucleic acids from a mixture having different species of nucleic acids other than circular nulceic acids wherein the mixture is treated under alkaline conditions at a PH>8 with a solid matrix consisting essentially of a silica material in presence of at least one chaotropic substance.
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