Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-15 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6824 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2001-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bf56f735eb93dd612588efae09c1ee5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f11e28cc503a51db247de2309ff1a23f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bd6e8f2f3d1d1a793155f7c5cb257ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5c9d7fbc07c57d9ae62df02642b09f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7629e2789dd6fcb1bb3f2473b61aa2e7 |
publicationDate |
2003-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2003032056-A1 |
titleOfInvention |
Peptide fragmentation |
abstract |
The present invention relates to a method of identifying a polypeptide using a class of novel, water-stable reagents. More specifically, the method according to the invention comprises the steps of n (a) derivatization in an aqueous solution of the N-terminus of the polypeptide, or the N-termini of one or more peptides of the polypeptide, with at least one acidic reagent which comprises a sulfonyl moiety coupled to an activated acid moiety to provide one or more peptide derivatives; n (b) analyzing at least one such derivative using a mass spectrometric technique to provide a fragmentation pattern; and n (c) interpreting the fragmentation pattern. n Furthermore, the present invention also relates to a kit for identifying a polypeptide by a mass spectrometric technique, which kit comprises at least one acidic reagent comprising a sulfonyl moiety coupled to an activated acid moiety in a container together with suitable means for analysis of the fragmentation pattern obtained. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112239453-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006014210-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006014293-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7371514-B2 |
priorityDate |
2001-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |