http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003013635-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-66 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 2002-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e485ce4c36d29956fc382d1aef1e29b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf189a0dcd691c80e0d8db0c2a5b5d6b |
| publicationDate | 2003-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2003013635-A1 |
| titleOfInvention | Method for the treatment of depression by inhibition of NAALADase |
| abstract | A method of treating depression and depression disorders which includes administering a pharmaceutically effective amount of one or more NAALADase inhibitors to a patient. NAALADase is an enzyme that hydrolyzes the peptide NAAG, a good peptide neurotransmitter in the brain. NAAG competes with the excitatory amino acid Glu. The excitatory amino acid Glu is released in the brain upon stress and can lead to depression. Hence, the inhibition of NAALADase directly decreases levels of Glu while increasing NAAG levels, contributes to and decreases depression. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012094472-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012094472-A3 |
| priorityDate | 2001-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.