abstract |
Heterocyclic compounds of formula (I), n n n wherein R 1 represents a hydrogen atom or a —(CH 2 ) M —Y group, wherein m is an integer from 0 to 4 and Y represents an alkyl, haloalkyl, alkoxy, alkoxycarbonyl, C 3 -C 7 cycloalkyl, norbornyl or phenylalkenyl group, or an aromatic group which aromatic group ^ may optionally be substituted by one or more halogen atoms; R 2 represents an aromatic group which aromatic group may optionally be substituted by one or more halogen atoms or alkyl, alkoxy, C 3 -C 6 cycloalkoxy, methylenedioxy, nitro, dialkylamino or trifluoromethyl groups, and R 3 represents a hydrogen or halogen atom or an alkyl group, and pharmaceutically acceptable salts thereof, processes for preparing the same. The compounds are phosphodiesterase 4 inhibitors. |