| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b011e77b33662b8bf1f2ff2de7b661 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4354
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0003 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2002-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f00c14c03f3685b8ade6af4bbc141d39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4dea863b71e23b7dea538622ac87ad0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_190e01ec43b6480b88601a32e545068a |
| publicationDate |
2002-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2002176862-A1 |
| titleOfInvention |
Parasite-derived anti-inflammatory immunomodulatory protein |
| abstract |
A protein with anti-inflammatory, and immunomodulatory functions was identified and isolated from the excretory/secretions of a human parasite, Schistosoma mansoni. This protein, designated herein as Sm 16.8, is released by schistosomes upon entry into human skin. Under in vitro conditions Sm 16.8 is shown to stimulate the production of anti-inflammatory cytokine Interleukin-1 receptor antagonist (IL-1ra) in human keratinocytes and transcriptionally down regulate the production of pro-inflammatory cytokines IL-1 and IL-1. |
| priorityDate |
1996-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |