http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002173465-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8114 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-57 |
| filingDate | 2002-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee03fda7f6067ec070fe5b7a9253da74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fa8771066f50544996ccb6275dad9fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b73dc844d9926e17b98a1fe8ed5e662a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d82ce03c2eb0af836d9597e75092803c |
| publicationDate | 2002-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2002173465-A1 |
| titleOfInvention | Compositions and methods for inhibiting cellular proliferation comprising TFPI fragments |
| abstract | Compositions and methods effective in inhibiting abnormal or undesirable cell proliferation, particularly endothelial cell proliferation and angiogenesis related to neovascularization and tumor growth are provided. The compositions comprise a naturally occurring or synthetic protein, peptide, or protein fragment containing all or an active portion of the C-terminal portion of proteinase inhibitors such as TFPI. The methods involve administering to a human or animal the composition described herein in a dosage sufficient to inhibit cell proliferation, particularly endothelial cell proliferation. The methods are useful for treating diseases and processes mediated by undesired and uncontrolled cell proliferation, such as cancer, particularly by inhibiting angiogenesis. Administration of the composition to a human or animal having prevascularized, metastasized tumors is useful for preventing the growth or expansion of such tumors. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2766036-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2012323928-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011036445-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009013075-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10239933-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009013075-A2 |
| priorityDate | 1997-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.