| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2002-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85826d9faad6a81daab5137e548e0fc8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70a9a4ddf74990a407470f4c5ac4dab5 |
| publicationDate |
2002-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2002172990-A1 |
| titleOfInvention |
Cyclin dependent kinase 5 phosphorylation of disabled 1 protein |
| abstract |
The present invention is based on the discovery that the Disabled 1 protein (Dab1) is a substrate for Cdk5 activity, and is selectively phosphorylated by Cdk5. An assay to determine Cdk5 activity by detection of Dab1 phosphorylation on serine amino acids that are selectively phosphorylated by Cdk5 is provided. The invention further provides an antibody and screening kit to determine Cdk5 activity, a method for detecting a neurological disorder by determining Cdk5 activity, a method of screening for compounds that increase or decrease Cdk5 activity and a method for treating a neurological disorder with such a compound. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114917414-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8822171-B1 |
| priorityDate |
2002-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |