| abstract |
The synthesis and the use of a series of carboplatin analogs is disclosed. These carboplatin analogs may be represented by cis-Pt(II)L 1 L 2 , wherein each of L 1 and L 2 , independently, is the carboxylate of phosphatidylserine, an α-amino acid, a β-amino acid, or a derivative thereof, wherein each ligand is bidentate with —NH 2 and —COO − as the binding sites. The complexes can be used in the treatment of cancer. |