http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002164390-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-07 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 |
| filingDate | 2001-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e90f2d6542422195db52cd7c5521800d |
| publicationDate | 2002-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2002164390-A1 |
| titleOfInvention | Compositions containing an active fraction isolated from tricholoma conglobatum and methods of use |
| abstract | This invention provides processes for isolating pharmaceutically active extracts, fractions and compounds from the mushroom Tricholoma Conglobatum. In one aspect, a homogenate of Tricholoma Conglobatum is extracted from a fraction isolated by column chromatography. It has an optical absorbance between about 210 nm and about 350 nm and is not heat stable. The active compound, having a molecular weight from about 18 to about 20 kD on SDS-PAGE gel, in the extract is further provided by this invention. A second active fraction isolated from the homogenate of Tricholoma Conglobatum can be further processed to separate into two additionally active compounds each of which has characteristics consistent with that of a protein. The fractions, compounds and extracts are useful to inhibit the growth of endothelial cells and to inhibit vascularization in a tissue. Methods of treating various diseases, including cancer, are also provided herein. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-6898535-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021255835-A1 |
| priorityDate | 2000-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 170.