Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_321601ebffa1b60386256ef6ac8b08ec |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-829 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
2001-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab98375d5e08af3b57dda321cb16500e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9567a8e911e416b3d91965222f551fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84e23dc99951e34c5e91afcd56cad147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e0f6e1562459501340600f36a11c3b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27a027ff74651eddce60039e730a1c01 |
publicationDate |
2002-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2002160038-A1 |
titleOfInvention |
Liposomes containing oligonucleotides |
abstract |
It is possible to radiosensitize tumor cells by administration of compositions containing the Human antisense c-raf- 1 oligodeoxyribonucleotide (ODN/oligo) sequence: 5 ′-GTGCTCCATTGATGC- 3 ′ (seq. # 1 ) wherein only the end bases are phosphorylated is a preferred embodiment. Antisense sequences of up to 40 bases which containing this sequence may be used in accord with the teachings of this disclosure. Compositions comprising a cationic liposome of dimethyldioctadecyl ammonium bromide, phosphatidylcholine and cholesterol may be used as a carrier system. The liposomes provide a new carrier system that is particularly useful for administration of sequences for therapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9035039-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009129319-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017176596-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016054421-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4104854-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017147540-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013075132-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016197132-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011160062-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017019891-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012106490-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2395012-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009082817-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10849975-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014046983-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2770057-A1 |
priorityDate |
1997-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |